Religious people are posting this image on their walls and pages unironically as an inspirational photo.
What they're missing is that the pic ('shopped, natch) is actually a reference to the infamous and incomprehensibly gross 'goatse' image. If you don't know what that is, don't look it up. Just check out the Snopes page, or use your imagination: Instead of hands stretching a hole in the clouds, think 'giant gaping rectum'.
I think the 'goatse cloud' image might be a perfect analogy (sorry) for religion in general. Some people find inspiration in it, but it's just something that someone made up. There's nobody in the sky, but if there were, he'd be a huge asshole.